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Summary: Those who drank sweetened coffee daily were up to 31% less likely to die within 7 years of follow-up compared to non-coffee drinkers. Those who drank unsweetened coffee were 21% less likely to die during follow-up.
source: American College of Physicians
A cohort study found that, compared to non-coffee drinkers, adults who drank moderate amounts (1.5 to 3.5 cups per day) of either unsweetened coffee or sugar-sweetened coffee were less likely to die during a 7-year follow-up period.
The results for those who used artificial sweeteners were less clear.
The results have been published in Annals of Internal Medicine.
Previous studies that monitored the health effects of coffee found that coffee consumption was associated with a lower risk of death but did not distinguish between unsweetened coffee and coffee consumed with sugar or artificial sweeteners.
Researchers from Southern Medical University in Guangzhou, China, used data from the UK Biobank Study Health Behavior Questionnaire to assess associations of sugar-sweetened, artificially sweetened, and unsweetened coffee consumption with all-cause and cause-specific death.
Over 171,000 participants from the UK who were not known to have heart disease or cancer were asked several questions related to dietary and health behavior to determine their coffee consumption habits.
- The authors found that during the 7-year follow-up period, participants who drank any amount of unsweetened coffee were 16 to 21% less likely to die than participants who did not drink coffee.
- They also found that participants who drank 1.5 to 3.5 cups per day of sugar-sweetened coffee were 29 to 31% less likely to die compared to participants who did not drink coffee.
- The authors note that adults who drank sugar-sweetened coffee added only about 1 teaspoon of sugar per cup of coffee on average.
- The results were inconclusive for participants who used artificial sweeteners in their coffee.
Any accompanying editorial by my editors Annals of internal medicine He notes that while coffee has qualities that could make health benefits possible, confounding variables including difficulty measuring differences in socioeconomic status, diet and other lifestyle factors may influence the results.

The authors add that the participants’ data is at least 10 years old and collected from a country where tea is a similarly popular beverage.
They caution that the average daily amount of sugar per cup of coffee recorded in this analysis is much lower than that of specialty drinks at popular coffee chain restaurants, and many coffee consumers may be drinking it in place of other beverages that make comparison with non-coffee drinkers more difficult. .
Based on this data, clinicians can tell their patients that there is no need for most coffee drinkers to eliminate the beverage from their diet but that caution should be exercised about higher-calorie coffees.
About this coffee and news of mortality research
author: press office
source: American College of Physicians
Contact: Press Office – American College of Physicians
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original search: Access closed.
“Association of consumption of sugar-sweetened, artificially sweetened, and unsweetened coffee with all-cause and cause-specific mortality.Written by Dan Liu et al. Annals of internal medicine
Access closed.
“Potential health benefits of coffee: Does filling a spoonful of sugar help flush it out?Written by Christina C. Wee. Annals of internal medicine
Summary
Association of consumption of sugar-sweetened, artificially sweetened, and unsweetened coffee with all-cause and cause-specific mortality.
background:
Previous observational studies suggested an association between coffee intake and a reduced risk of death, but these studies did not distinguish between coffee consumed with sugar or artificial sweeteners and coffee consumed without.
Goal:
To evaluate the associations of consumption of sugar-sweetened, artificially sweetened, and unsweetened coffee with all causes of death and cause-specific.
design:
A prospective cohort study.
Adjust:
Data were extracted from the UK Biobank.
Participants:
A total of 171,616 participants (mean age, 55.6 years [SD, 7.9]) without cardiovascular disease (CVD) or cancer at baseline were eligible. Baseline demographic, lifestyle and diet data from the UK Biobank were used, with follow-up starting in 2009 and ending in 2018.
Measurements:
Dietary consumption of sugar-sweetened, artificially sweetened, and unsweetened coffee has been reported. All-cause, cancer-related and cardiovascular mortality were estimated.
consequences:
During a follow-up of 7.0 years, 3,177 deaths were recorded (including 1,725 cancer deaths and 628 cardiovascular deaths). Cox’s punished slice models showed U-shaped associations of unsweetened coffee, sugar-sweetened coffee, and artificially sweetened coffee with mortality. Compared to non-consumers, consumers of different amounts of unsweetened coffee (>0 to 1.5, >1.5 to 2.5, >2.5 to 3.5, >3.5 to 4.5, >4.5 drinks/day) had a lower risk of all-cause death after lifestyle modification, and sociodemographic, and clinical factors, with hazard ratios each of 0.79 (95% CI, 0.70 to 0.90), 0.84 (CI, 0.74 to 0.95), 0.71 (CI, 0.62 to 0.82), 0.71 (CI, 0.60 to 0.84), and 0.77 (CI, 0.65 to 0.91); Estimates for consumption of sugar-sweetened coffee were 0.91 (CI, 0.78 to 1.07), 0.69 (CI, 0.57 to 0.84), 0.72 (CI, 0.57 to 0.91), 0.79 (CI, 0.60 to 1.06), 1.05 (CI, 0.82 to 1.36). ). The association between artificially sweetened coffee and mortality was less consistent. The association between coffee drinking and mortality from cancer and CVD was largely consistent with all causes of mortality. U-shaped correlations were also observed for instant, ground, and decaffeinated coffee.
Restriction:
Exposure assessed at baseline may not capture changes in intake over time.
conclusion:
Moderate consumption of unsweetened and sugar-sweetened coffee was associated with a lower risk of death.
Primary funding source:
The National Natural Science Foundation of China, the Young Elite Scholars Program by CAST, and the project supported by the Guangdong Basic and Applied Basic Research Foundation.
Summary
Potential health benefits of coffee: Does filling a spoonful of sugar help flush it out?
Coffee is one of the most consumed beverages, and there has been a long-standing interest in understanding its health effects.
According to a 2022 estimate, Americans drink 517 million cups of coffee per day, and 66% of Americans surveyed reported having drank coffee within the past day.
Much of the data to date on the health effects of coffee is based on observational studies, and these—including two previous studies published by Annals in 2017 by Gunter and colleagues and Park and colleagues—suggest a U-shaped relationship between coffee consumption and all-cause mortality. other health outcomes; Those who consume moderate amounts of coffee daily.
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